HepatiCan Limited
Making a transformative and disruptive change to the care of patients with acute/severe liver failure.
HepatiCan Limited
Making a transformative and disruptive change to the care of patients with acute/severe liver failure.
Making a transformative and disruptive change to the care of patients with acute/severe liver failure.
Making a transformative and disruptive change to the care of patients with acute/severe liver failure.
1 million people die each year from liver disease (Acute and Chronic Liver Failure) Worldwide and only 1 in 10 people who need a liver transplant will get one. HepatiCan has developed a novel ATMP and device – BioArtificial Liver - to rescue patients with Acute Liver Failure (‘ALF’). ALF is an unmet medical need with an addressable market in Europe of £5.7 – 7 billion. The HepatiCan system employs a cryo-preservable, single use cartridge, which means treatment can be initiated in 24h unlike other cell therapy solutions. The HepatiCan system’s preclinical data has delivered proof of concept with the product at clinical scale and has received Orphan Drug Designation (ODD) in EMA and FDA jurisdictions.
The biocartridge is cryo-preservable and single use and the biomass is available from frozen in less than a day. With the device already at a clinical scale of 70 billion cells as organoids, it holds 3 patent families and a manufacturing know how, and has an Orphan Drug Designation (ODD) in EMA and FDA jurisdictions.
The HepatiCan device interfaces with an existing standard of care equipment and works as an out-of-body healthy liver, allowing for a patient’s recovery before/instead of liver transplantation and any patient-facing items are designed as disposables.